Functional Role of the L396R Mutation of Tks5 Identified by an Exome-Wide Association Study in Atrial Fibrillation.

doi:10.1253/circj.CJ-20-0101

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Functional Role of the L396R Mutation of Tks5 Identified by an Exome-Wide Association Study in Atrial Fibrillation.

Circulation journal : official journal of the Japanese Circulation Society - 25 Nov 2020

Yang Xiaoxi, Sasano Tetsuo, Ebana Yusuke, Takeuchi Jun K, Ihara Kensuke, Yamazoe Masahiro, Furukawa Tetsushi

Abstract excerpt

BACKGROUND: Atrial fibrillation (AF) is the most common cardiac arrhythmia; however, the current treatment strategies for AF have limited efficacy. Thus, a better understanding of the mechanisms underlying AF is important for future therapeutic strategy. A previous study (Exome-Wide Association Study (ExWAS)) identified a rare variant, rs202011870 (MAF=0.00036, GenomAD), which is highly associated with AF...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adaptor Proteins, Vesicular Transport

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Atrial Fibrillation

Share to Cell Movement

Share to Exome

Share to Inflammation

Share to Mice

Share to Mutation

Share to RAW 264.7 Cells

Source

Open in PubMed

Identifiers

PMID: 33087629
DOI: 10.1253/circj.CJ-20-0101

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional Role of the L396R Mutation of Tks5 Identified by an Exome-Wide Association Study in Atrial Fibrillation.PMID 33087629Read ↗

Discovery of <em>SOX5</em> as a New Causative Gene for Atrial FibrillationSemantic proximity Read ↗

Prevalence and Spectrum of TBX5 Mutation in Patients with Lone Atrial Fibrillation.Semantic proximity Read ↗

Prevalence and spectrum of GJA5 mutations associated with lone atrial fibrillation.Semantic proximity Read ↗

Mutational spectrum of the NKX2-5 gene in patients with lone atrial fibrillation.Semantic proximity Read ↗

Novel KCNA5 loss-of-function mutations responsible for atrial fibrillation.Semantic proximity Read ↗

Atrial fibrillation risk model based on LASSO and SVM algorithms and immune infiltration of key mitochondrial energy metabolism genesSemantic proximity Read ↗

KLF15 Loss-of-Function Mutation Underlying Atrial Fibrillation as well as Ventricular Arrhythmias and Cardiomyopathy.Semantic proximity Read ↗

TBX5 loss-of-function mutation contributes to atrial fibrillation and atypical Holt-Oram syndrome.Semantic proximity Read ↗

Novel GATA5 loss-of-function mutations underlie familial atrial fibrillationSemantic proximity Read ↗

A novel GATA5 loss-of-function mutation underlies lone atrial fibrillation.Semantic proximity Read ↗

Fibroblast growth factor 5 as a target for atrial fibrillation treatment: Evidence from mendelian randomization.Semantic proximity Read ↗

Circulating exosome long non-coding RNAs are associated with atrial structural remodeling by increasing systemic inflammation in atrial fibrillation patientsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.