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Article

The transcription factor Sox10 is an essential determinant of branching morphogenesis and involution in the mouse mammary gland.

Scientific reports - 20 Oct 2020

Mertelmeyer Svenja, Weider Matthias, Baroti Tina, Reiprich Simone, Fröb Franziska, Stolt C Claus, Wagner Kay-Uwe, Wegner Michael

Abstract excerpt

The high mobility group-domain containing transcription factor Sox10 is an essential regulator of developmental processes and homeostasis in the neural crest, several neural crest-derived lineages and myelinating glia. Recent studies have also implicated Sox10 as an important factor in mammary stem and precursor cells. Here we employ a series of mouse mutants with constitutive and conditional Sox10 deficiencies...

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Source

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Identifiers

PMID: 33082503
DOI: 10.1038/s41598-020-74664-y
PMCID: PMC7575560

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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