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Transcriptional and proteomic insights into the host response in fatal COVID-19 cases

20 Oct 2020

Abstract excerpt

Coronavirus disease 2019 (COVID-19), the global pandemic caused by SARS-CoV-2, has resulted thus far in greater than 933,000 deaths worldwide; yet disease pathogenesis remains unclear. Clinical and immunological features of patients with COVID-19 have highlighted a potential role for changes in immune activity in regulating disease severity. However, little is known about the responses in human lung tissue, the...

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PMID: 33082228
DOI: 10.1073/pnas.2018030117

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