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Article

Slc39a5-mediated zinc homeostasis plays an essential role in venous angiogenesis in zebrafish.

Open biology - 1 Oct 2020

Xia Zhidan, Bi Xinying, Lian Jia, Dai Wei, He Xuyan, Zhao Lu, Min Junxia, Wang Fudi

Abstract excerpt

Angiogenesis is a precise process mediated by a variety of signals and the environmental niche. Although the essential trace element zinc and its homeostasis are essential for maintaining proper cellular functions, whether zinc plays a role in angiogenesis is currently unknown. Using zebrafish embryos as a model system, we found that zinc treatment significantly increased the expression of the slc39a5 gene, which...

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Identifiers

PMID: 33081634
DOI: 10.1098/rsob.200281
PMCID: PMC7653363

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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