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CDR3 sequences in IgA nephropathy are shorter and exhibit reduced diversity

17 Oct 2020

Abstract excerpt

Immunoglobulin (Ig) A nephropathy (IgAN) is the most common glomerulonephritis, which is characterized by the deposition of IgA antibody in the glomerulus. Systematic dissection of immune composition may contribute to a better understanding of the alternations in the immune system in IgAN. To this end, here we applied immune repertoire sequencing technology for parallel analysis of the complementary determining...

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PMID: 33067920
DOI: 10.1002/2211-5463.13006

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