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Functional connectivity of white matter as a biomarker of cognitive decline in Alzheimer’s disease

16 Oct 2020

Abstract excerpt

OBJECTIVE: In vivo functional changes in white matter during the progression of Alzheimer's disease (AD) have not been previously reported. Our objectives are to measure changes in white matter functional connectivity (FC) in an elderly population undergoing cognitive decline as AD develops, to establish their relationship to neuropsychological scores of cognitive abilities, and to assess the performance in...

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PMID: 33064765
DOI: 10.1371/journal.pone.0240513

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