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Article

Intracellular optical doppler phenotypes of chemosensitivity in human epithelial ovarian cancer.

Scientific reports - 15 Oct 2020

Li Zhe, An Ran, Swetzig Wendy M, Kanis Margaux, Nwani Nkechiyere, Turek John, Matei Daniela, Nolte David

Abstract excerpt

Development of an assay to predict response to chemotherapy has remained an elusive goal in cancer research. We report a phenotypic chemosensitivity assay for epithelial ovarian cancer based on Doppler spectroscopy of infrared light scattered from intracellular motions in living three-dimensional tumor biopsy tissue measured in vitro. The study analyzed biospecimens from 20 human patients with epithelial ovarian...

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Share to Antineoplastic Agents
Share to Carcinoma, Ovarian Epithelial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Resistance, Neoplasm

Share to Ovarian Neoplasms

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Share to Tumor Microenvironment

Share to Ultrasonography, Doppler

Source

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Identifiers

PMID: 33060663
DOI: 10.1038/s41598-020-74336-x
PMCID: PMC7562924

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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