Article
Biodynamic imaging for phenotypic profiling of three-dimensional tissue culture.
Journal of biomedical optics - 1 Jan 2017
Sun Hao, Merrill Daniel, An Ran, Turek John, Matei Daniela, Nolte David D
Abstract excerpt
Three-dimensional (3-D) tissue culture represents a more biologically relevant environment for testing new drugs compared to conventional two-dimensional cancer cell culture models. Biodynamic imaging is a high-content 3-D optical imaging technology based on low-coherence interferometry and digital holography that uses dynamic speckle as high-content image contrast to probe deep inside 3-D tissue. Speckle...
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