Article
Evaluation of the Pathogenicity and the Escape from Vaccine Protection of a New Antigenic Variant Derived from the European Human-Like Reassortant Swine H1N2 Influenza Virus.
Viruses - 12 Oct 2020
Deblanc Céline, Quéguiner Stéphane, Gorin Stéphane, Chastagner Amélie, Hervé Séverine, Paboeuf Frédéric, Simon Gaëlle
Abstract excerpt
The surveillance of swine influenza A viruses in France revealed the emergence of an antigenic variant following deletions and mutations that are fixed in the HA-encoding gene of the European human-like reassortant swine H1N2 lineage. In this study, we compared the outcomes of the parental (H1huN2) and variant (H1huN2Δ146-147) virus infections in experimentally-inoculated piglets. Moreover, we assessed and...
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