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Genetic and Antigenic Evolution of European Swine Influenza A Viruses of HA-1C (Avian-Like) and HA-1B (Human-Like) Lineages in France from 2000 to 2018.

Viruses - 13 Nov 2020

Chastagner Amélie, Hervé Séverine, Quéguiner Stéphane, Hirchaud Edouard, Lucas Pierrick, Gorin Stéphane, Béven Véronique, Barbier Nicolas, Deblanc Céline, Blanchard Yannick, Simon Gaëlle

Abstract excerpt

This study evaluated the genetic and antigenic evolution of swine influenza A viruses (swIAV) of the two main enzootic H1 lineages, i.e., HA-1C (H1av) and -1B (H1hu), circulating in France between 2000 and 2018. SwIAV RNAs extracted from 1220 swine nasal swabs were hemagglutinin/neuraminidase (HA/NA) subtyped by RT-qPCRs, and 293 virus isolates were sequenced. In addition, 146 H1avNy and 105 H1huNy strains were...

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PMID: 33202972
DOI: 10.3390/v12111304
PMCID: PMC7697621

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