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Article

Contribution of Genetics to the Susceptibility to Hidradenitis Suppurativa in a Large, Cross-sectional Dutch Twin Cohort.

JAMA dermatology - 1 Dec 2020

van Straalen Kelsey R, Prens Errol P, Willemsen Gonneke, Boomsma Dorret I, van der Zee H H

Abstract excerpt

Importance: Hidradenitis suppurativa is a chronic, inflammatory skin disease in which genetic factors are considered to play a role, with up to 38% of patients reporting a family history. Variations in the γ-secretase genes are found mainly in familial cases with an autosomal dominant pattern of inheritance. These variations are rare in the general population with hidradenitis suppurativa, even in patients who...

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Identifiers

PMID: 33052394
DOI: 10.1001/jamadermatol.2020.3630
PMCID: PMC7557497

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Contribution of Genetics to the Susceptibility to Hidradenitis Suppurativa in a Large, Cross-sectional Dutch Twin Cohort.PMID 33052394Read ↗

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