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Sirt1 regulates testosterone biosynthesis in Leydig cells via modulating autophagy

13 Oct 2020

Abstract excerpt

Dear Editor, Steroid hormones are crucial signal molecules that regulate a large number of physiological and developmental processes. Testosterone is the key steroid hormone required for the development of male characteristics and also supports the physiology of the male reproductive system (Sinclair et al., 2015). Testosterone is primarily produced by the Leydig cells residing in the testicular interstitium. The...

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PMID: 33048320
DOI: 10.1007/s13238-020-00771-1

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