Article
Contribution of functional dopamine D2 and D3 receptor variants to motor and non-motor symptoms of early onset Parkinson's disease.
Clinical neurology and neurosurgery - 1 Dec 2020
Eryilmaz Isil Ezgi, Erer Sevda, Zarifoglu Mehmet, Egeli Unal, Karakus Ece, Yurdacan Beste, Cecener Gulsah, Tunca Berrin, Colakoglu Beril, Bora Tokcaer Ayse, Saka Esen, Demirkiran Meltem, Akbostanci Cenk, Dogu Okan, Kaleagasi Hakan, Kenangil Gulay, Cakmur Raif, Elibol Bulent
Abstract excerpt
In the present study, we focused on investigating the contribution of functional dopamine D2 and D3 receptor variants to motor and/or non-motor symptoms of early onset Parkinson's disease (EOPD). Three functional single nucleotide polymorphisms (SNPs), DRD3 rs6280, DRD2 rs2283265 and DRD2 rs1076560, were genotyped in 128 Turkish EOPD patients and then, statistical analysis was conducted for the potential impacts...
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