Article
Overexpression of RAD50 is the Marker of Poor Prognosis and Drug Resistance in Breast Cancer Patients.
Current cancer drug targets - 1 Jan 2021
Karamat Uzma, Ejaz Samina
Abstract excerpt
BACKGROUND: The prevalence of breast cancer is increasing at an alarming rate and thus demands exploration of the most relevant diagnostic biomarkers. RAD50 is a cancer susceptibility gene that encodes a DNA damage repairing protein. Its role in breast cancer as clinico-pathological specific biomarker has yet to be explored. OBJECTIVE: This study was aimed to investigate the RAD50 expression and its promoter's...
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