Article
Pregnancy does not modify the risk of MS in genetically susceptible women.
Neurology(R) neuroimmunology & neuroinflammation - 1 Nov 2020
Adams Cameron J, Wu Sean L, Shao Xiaorong, Bradshaw Patrick T, Gonzales Edlin, Smith Jessica B, Xiang Anny H, Bellesis Kalliope H, Chinn Terrence, Bos Steffan D, Wendel-Haga Marte, Olsson Tomas, Kockum Ingrid, Langer-Gould Annette M, Schaefer Catherine, Alfredsson Lars, Barcellos Lisa F
Abstract excerpt
OBJECTIVE: To use the case-only gene-environment (G [Formula: see text] E) interaction study design to estimate interaction between pregnancy before onset of MS symptoms and established genetic risk factors for MS among White adult females. METHODS: We studied 2,497 female MS cases from 4 cohorts in the United States, Sweden, and Norway with clinical, reproductive, and genetic data. Pregnancy exposure was defined...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.