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Article

MicroRNA‐34a‐5p Promotes Joint Destruction During Osteoarthritis

8 Oct 2020

Abstract excerpt

OBJECTIVE: MicroRNA-34a-5p (miR-34a-5p) expression is elevated in the synovial fluid of patients with late-stage knee osteoarthritis (OA); however, its exact role and therapeutic potential in OA remain to be fully elucidated. This study was undertaken to examine the role of miR-34a-5p in OA pathogenesis. METHODS: Expression of miR-34a-5p was determined in joint tissues and human plasma (n = 71). Experiments using...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33034147
DOI: 10.1002/art.41552

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