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Article

MicroRNA-33a regulates cholesterol synthesis and cholesterol efflux-related genes in osteoarthritic chondrocytes

4 Mar 2015

Abstract excerpt

INTRODUCTION: Several studies have shown that osteoarthritis (OA) is strongly associated with metabolism-related disorders, highlighting OA as the fifth component of the metabolic syndrome (MetS). On the basis of our previous findings on dysregulation of cholesterol homeostasis in OA, we were prompted to investigate whether microRNA-33a (miR-33a), one of the master regulators of cholesterol and fatty acid...

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Share to Cholesterol and Lipid Metabolism
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PMID: 25880168
DOI: 10.1186/s13075-015-0556-y

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