Article
RMVar: an updated database of functional variants involved in RNA modifications.
Nucleic acids research - 8 Jan 2021
Luo Xiaotong, Li Huiqin, Liang Jiaqi, Zhao Qi, Xie Yubin, Ren Jian, Zuo Zhixiang
Abstract excerpt
Distinguishing the few disease-related variants from a massive number of passenger variants is a major challenge. Variants affecting RNA modifications that play critical roles in many aspects of RNA metabolism have recently been linked to many human diseases, such as cancers. Evaluating the effect of genetic variants on RNA modifications will provide a new perspective for understanding the pathogenic mechanism of...
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