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Article

The StkP/PhpP signaling couple in Streptococcus pneumoniae: cellular organization and physiological characterization.

Journal of bacteriology - 1 Aug 2009

Osaki Makoto, Arcondéguy Tania, Bastide Amandine, Touriol Christian, Prats Hervé, Trombe Marie-Claude

Abstract excerpt

In Streptococcus pneumoniae, stkP and phpP, encoding the eukaryotic-type serine-threonine kinase and PP2C phosphatase, respectively, form an operon. PhpP has the features of a so-called "soluble" protein, whereas StkP protein is membrane associated. Here we provide the first genetic and physiological evidence that PhpP and StkP, with antagonist enzymatic activities, constitute a signaling couple. The StkP-PhpP...

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Source

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Identifiers

PMID: 19502404
DOI: 10.1128/JB.00196-09
PMCID: PMC2715703

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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