Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mast Cell Promotes the Development of Intracranial Aneurysm Rupture.

Stroke - 1 Nov 2020

Furukawa Hajime, Wada Kosuke, Tada Yoshiteru, Kuwabara Atsushi, Sato Hiroki, Ai Jinglu, Lawton Michael T, Hashimoto Tomoki

Abstract excerpt

BACKGROUND AND PURPOSE: Inflammation has emerged as a key component of the pathophysiology of intracranial aneurysms. Mast cells have been detected in human intracranial aneurysm tissues, and their presence was associated with intramural microhemorrhage and wall degeneration. We hypothesized that mast cells play a critical role in the development of aneurysmal rupture, and that mast cells can be used as a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chymases
Share to Intracranial Aneurysm
Share to Mast Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Matrix Metalloproteinase 9

Share to Proto-Oncogene Proteins c-kit

Share to Receptor, Angiotensin, Type 1

Share to Subarachnoid Hemorrhage

Share to Tryptases

Source

Open in PubMed Open full text

Identifiers

PMID: 33019897
DOI: 10.1161/STROKEAHA.120.030834
PMCID: PMC7606717

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mast Cell Promotes the Development of Intracranial Aneurysm Rupture.PMID 33019897Read ↗

Biology of Intracranial Aneurysms: Role of InflammationSemantic proximity Read ↗

Intracranial Aneurysm as a Macrophage-mediated Inflammatory DiseaseSemantic proximity Read ↗

Involvement of neutrophils in machineries underlying the rupture of intracranial aneurysmsSemantic proximity Read ↗

A role for inflammation in intracranial aneurysm pathophysiology?Semantic proximity Read ↗

Smooth Muscle Peroxisome Proliferator-Activated Receptor γ Plays a Critical Role in Formation and Rupture of Cerebral Aneurysms in Mice In Vivo.Semantic proximity Read ↗

The Role of Inflammation and Myeloperoxidase-Related Oxidative Stress in the Pathogenesis of Genetically Triggered Thoracic Aortic Aneurysms.Semantic proximity Read ↗

Investigation and Modulation of Interleukin 6 following Subarachnoid Hemorrhage: Targeting Inflammatory Activation for Cerebral VasospasmSemantic proximity Read ↗

SAH and inflammation: Inflammatory Mechanisms after SAH (EBI and or Vasospasm)Semantic proximity Read ↗

Aneurysm formation in proinflammatory, transgenic haptoglobin 2-2 mice.Semantic proximity Read ↗

Enhancing Th17 cells drainage through meningeal lymphatic vessels alleviate neuroinflammation after subarachnoid hemorrhageSemantic proximity Read ↗

M1 macrophages are required for murine cerebral aneurysm formation.Semantic proximity Read ↗

Impact of monocyte chemoattractant protein-1 deficiency on cerebral aneurysm formation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.