Article
CREB1 and BDNF gene polymorphisms are associated with early treatment response to escitalopram in panic disorder.
Journal of affective disorders - 1 Jan 2021
Yang Junfeng, Li Shen, Lv Hao, Wang Wenchen, Zhang Jian, Chu Lijun, Zhang Yong
Abstract excerpt
OBJECTIVES: Increasing evidence shows that the alternations under escitalopram treatment for Panic disorder (PD) patients are related to the cAMP response element-binding protein (CREB) and brain-derived neurotrophic factor (BDNF). We aimed to explore the single nucleotide polymorphisms (SNPs) of genes BDNF and CREB1 in the treatment response to escitalopram on PD. METHODS: There were 80 PD patients with DSM-5...
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