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Correlation between cytochrome P450 2C19 genetic polymorphism and treatment response to escitalopram in panic disorder.

Pharmacogenetics and genomics - 1 Aug 2017

He Qianqian, Yuan Zhuo, Liu Yuanyuan, Zhang Jian, Yan Hong, Shen Li, Luo Xingguang, Zhang Yong

Abstract excerpt

OBJECTIVES: Escitalopram (S-CT) is used widely to treat patients with panic disorder (PD) and the CYP2C19 enzyme is responsible for S-CT metabolism. We hypothesized that CYP2C19 polymorphisms were associated with S-CT treatment response in Chinese patients with PD. PATIENTS AND METHODS: Seventy-eight patients with PD completed the assessment by the Panic Disorder Severity Scale - Chinese Version (PDSS-CV) and the...

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PMID: 28614176
DOI: 10.1097/FPC.0000000000000290

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