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Article

IntAPT: integrated assembly of phenotype-specific transcripts from multiple RNA-seq profiles.

Bioinformatics (Oxford, England) - 5 May 2021

Shi Xu, Neuwald Andrew F, Wang Xiao, Wang Tian-Li, Hilakivi-Clarke Leena, Clarke Robert, Xuan Jianhua

Abstract excerpt

MOTIVATION: High-throughput RNA sequencing has revolutionized the scope and depth of transcriptome analysis. Accurate reconstruction of a phenotype-specific transcriptome is challenging due to the noise and variability of RNA-seq data. This requires computational identification of transcripts from multiple samples of the same phenotype, given the underlying consensus transcript structure. RESULTS: We present a...

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PMID: 33016988
DOI: 10.1093/bioinformatics/btaa852
PMCID: PMC8097681

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