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Article

Genome-wide association study of cardiovascular disease in testicular cancer patients treated with platinum-based chemotherapy.

The pharmacogenomics journal - 1 Apr 2021

Steggink Lars C, Boer Hink, Meijer Coby, Lefrandt Joop D, Terstappen Leon W M M, Fehrmann Rudolf S N, Gietema Jourik A

Abstract excerpt

Genetic variation may mediate the increased risk of cardiovascular disease (CVD) in chemotherapy-treated testicular cancer (TC) patients compared to the general population. Involved single nucleotide polymorphisms (SNPs) might differ from known CVD-associated SNPs in the general population. We performed an explorative genome-wide association study (GWAS) in TC patients. TC patients treated with platinum-based...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 33011741
DOI: 10.1038/s41397-020-00191-8
PMCID: PMC7997802

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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