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FTO rs1121980 polymorphism contributes to coronary artery disease susceptibility in a Chinese Han population.

Lipids in health and disease - 2 Jan 2025

Min Xue, Zhou Yu-Lan, Qu Yun-Fei, Liao Zhao-Fu, Li Heng, Cheng Jie, Liang Li-Li, Mo Hai-Liang, Wu Zhu-Guo, Xiong Xing-Dong

Abstract excerpt

BACKGROUND: The fat mass and obesity-associated protein (FTO) has been showed to be involved in the pathogenesis and progression of coronary artery disease (CAD). However, the effects of FTO variants on CAD risk remain poorly understood. We herein genotyped three SNPs (rs1121980, rs72803657, and rs4783818) in FTO to investigate the influence of FTO polymorphisms on individual susceptibility to CAD. METHODS:...

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Identifiers

PMID: 39748419
DOI: 10.1186/s12944-024-02417-1
PMCID: PMC11697032

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