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Article

A Combination of Single-Nucleotide Polymorphisms Is Associated with Interindividual Variability in Cholecalciferol Bioavailability in Healthy Men.

The Journal of nutrition - 1 Dec 2016

Desmarchelier Charles, Borel Patrick, Goncalves Aurélie, Kopec Rachel, Nowicki Marion, Morange Sophie, Lesavre Nathalie, Portugal Henri, Reboul Emmanuelle

Abstract excerpt

BACKGROUND: Most people require dietary vitamin D to achieve the recommended concentration of 25-hydroxyvitamin D [25(OH)D] in the blood. However, the response to vitamin D supplementation is highly variable among individuals. OBJECTIVE: We assessed whether the variability in cholecalciferol bioavailability was associated with single-nucleotide polymorphisms (SNPs) in candidate genes. METHODS: In a single-group...

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Identifiers

PMID: 27798339
DOI: 10.3945/jn.116.237115

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