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The effects of common variants in MDM2 and GNRH2 genes on the risk and survival of osteosarcoma in Han populations from Northwest China.

Scientific reports - 29 Sept 2020

Feng Weilou, Wang Zhi, Feng Dongxu, Zhu Yangjun, Zhang Kun, Huang Wei

Abstract excerpt

Accumulating evidence has shown that both MDM2 and GNRH2 might be related to Osteosarcoma (OS) susceptibility. The study aimed to evaluate the effects of common variants in MDM2 and GNRH2 genes on the risk and survival of osteosarcoma in Han populations from Northwest China. In the study, we recruited 2292 subjects including 596 OS patients and 1696 healthy controls and genotyped 16 selected tag SNPs (6 from...

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Identifiers

PMID: 32994424
DOI: 10.1038/s41598-020-72995-4
PMCID: PMC7524757

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