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Article

A systematic review and meta-analysis of MDM2 polymorphisms in osteosarcoma susceptibility.

Pediatric research - 1 Oct 2016

Bilbao-Aldaiturriaga Nerea, Askaiturrieta Ziortza, Granado-Tajada Itsasne, Goričar Katja, Dolžan Vita, For The Slovenian Osteosarcoma Study Group, Garcia-Miguel Purificación, Garcia de Andoin Nagore, Martin-Guerrero Idoia, Garcia-Orad Africa

Abstract excerpt

Two polymorphisms in the murine double minute 2 (MDM2) gene (rs1690916 and rs2279744) have been associated with the risk of osteosarcoma (OS). When we analyzed these two polymorphisms in two new independents cohorts (Spanish and Slovenian), we found no association. In order to clarify this, we conducted a meta-analysis including six populations, with a total of 246 OS patients and 1,760 controls for rs1690916;...

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Source

Identifiers

PMID: 27438225
DOI: 10.1038/pr.2016.120

Genes

MDM2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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