Article
Genetic variants of lncRNA HOTAIR contribute to the risk of osteosarcoma.
Oncotarget - 12 Apr 2016
Zhou Quan, Chen Fengli, Fei Zhongting, Zhao Jiali, Liang Yong, Pan Wei, Liu Xingxiang, Zheng Donghui
Abstract excerpt
Osteosarcoma (OS) is the most common primary malignant bone tumor in adolescents and young adults. However, the essential mechanisms underlying osteosarcomagenesis remain obscure. The HOTAIR, a well-known long noncoding RNA (lncRNA), is involved in pathogenesis and progress of multiple tumors. To reveal the potential role of lncRNA HOTAIR in OS carcinogenesis, we conducted a two-stage, case-control study among...
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