Article
Liquid biopsy for ALK-positive early non-small-cell lung cancer predicts disease relapse.
Future oncology (London, England) - 1 Jan 2021
Li Ji, Dong Wen, Liu Li Na, Huang Yi Jiang, Xiao Mei Fang
Abstract excerpt
Background: We aimed to determine whether circulating tumor cells (CTCs) and cell-free DNA (cfDNA) aids in prognosis of relapse-free survival (RFS). Methods: Non-small cell lung cancer patients with ALK mutations were recruited prospectively. CTCs and cfDNA were quantified at different time points. RFS was estimated and correlated. Results: Baseline median CTCs and cfDNA were 16 cells and 57 ng/mL and declined to...
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