Article
RhD variants in Caucasians: consequences for checking clinically relevant alleles.
Transfusion - 1 Sept 2004
Ansart-Pirenne Hélène, Asso-Bonnet Marianne, Le Pennec Pierre-Yves, Roussel Michèle, Patereau Claude, Noizat-Pirenne France
Abstract excerpt
BACKGROUND: Weak D type carriers cannot be immunized against D except when antigen density is below 400 antigens per RBC, whereas partial D carriers can produce anti-D. STUDY DESIGN AND METHODS: A total of 168 blood samples from Caucasian individuals were studied because of weak D expression and/or anti-D production. Serologic analysis and molecular analysis were performed. RESULTS: In total, 70 partial D and 62...
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