Article
Sensory Glia Detect Repulsive Odorants and Drive Olfactory Adaptation.
Neuron - 25 Nov 2020
Duan Duo, Zhang Hu, Yue Xiaomin, Fan Yuedan, Xue Yadan, Shao Jiajie, Ding Gang, Chen Du, Li Shitian, Cheng Hankui, Zhang Xiaoyan, Zou Wenjuan, Liu Jia, Zhao Jian, Wang Linmei, Zhao Bingzhen, Wang Zhiping, Xu Suhong, Wen Quan, Liu Jie, Duan Shumin, Kang Lijun
Abstract excerpt
Glia are typically considered as supporting cells for neural development and synaptic transmission. Here, we report an active role of a glia in olfactory transduction. As a polymodal sensory neuron in C. elegans, the ASH neuron is previously known to detect multiple aversive odorants. We reveal that the AMsh glia, a sheath for multiple sensory neurons including ASH, cell-autonomously respond to aversive odorants...
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