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Article

Reciprocal inhibition between sensory ASH and ASI neurons modulates nociception and avoidance in Caenorhabditis elegans.

Nature communications - 13 Jan 2015

Guo Min, Wu Tai-Hong, Song Yan-Xue, Ge Ming-Hai, Su Chun-Ming, Niu Wei-Pin, Li Lan-Lan, Xu Zi-Jing, Ge Chang-Li, Al-Mhanawi Maha T H, Wu Shi-Ping, Wu Zheng-Xing

Abstract excerpt

Sensory modulation is essential for animal sensations, behaviours and survival. Peripheral modulations of nociceptive sensations and aversive behaviours are poorly understood. Here we identify a biased cross-inhibitory neural circuit between ASH and ASI sensory neurons. This inhibition is essential to drive normal adaptive avoidance of a CuSO4 (Cu(2+)) challenge in Caenorhabditis elegans. In the circuit, ASHs...

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PMID: 25585042
DOI: 10.1038/ncomms6655

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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