Article
Functional gene networks reveal distinct mechanisms segregating in migraine families.
Brain : a journal of neurology - 1 Oct 2020
Rasmussen Andreas H, Kogelman Lisette J A, Kristensen David M, Chalmer Mona Ameri, Olesen Jes, Hansen Thomas Folkmann
Abstract excerpt
Migraine is the most common neurological disorder worldwide and it has been shown to have complex polygenic origins with a heritability of estimated 40-70%. Both common and rare genetic variants are believed to underlie the pathophysiology of the prevalent types of migraine, migraine with typical aura and migraine without aura. However, only common variants have been identified so far. Here we identify for the...
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