Article
Treatment response of CNS high-grade neuroepithelial tumors with MN1 alteration.
Pediatric blood & cancer - 1 Dec 2020
Baroni Lorena V, Rugilo Carlos, Lubieniecki Fabiana, Sampor Claudia, Freytes Candela, Nobre Liana, Hansford Jordan R, Malalasekera Vajiranee S, Zapotocky Michal, Dodgshun Andrew, Martinez Ofelia Cruz, La Madrid Andres Morales, Lavarino Cinzia, Suñol Mariona, Rutkowski Stefan, Schuller Ulrich, Bouffet Eric, Ramaswamy Vijay, Alderete Daniel
Abstract excerpt
Central nervous system high-grade neuroepithelial tumor with MN1 alteration (CNS HGNET-MN1) is a rare recently described entity. Fourteen CNS HGNET-MN1 patients were identified using genome-wide methylation arrays/RT-PCR across seven institutions. All patients had surgery (gross total resection: 10; subtotal resection: four) as initial management followed by observation alone in three patients, followed by...
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