Article
Role of DNA Methylation Profile in Diagnosing Astroblastoma: A Case Report and Literature Review
30 Apr 2019
Abstract excerpt
Astroblastoma is a rare tumor of the central nervous system (CNS) with uncertain clinical behavior. Recently, DNA methylation profiling has been shown to provide a highly robust and reproducible approach for the classification of all CNS tumors across different age groups. By using DNA methylation profiling, a subset of CNS high-grade tumors with astroblastoma-like morphology characterized by the meningioma 1...
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