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Glioblastoma cell differentiation trajectory predicts the immunotherapy response and overall survival of patients

21 Sept 2020

Abstract excerpt

were the 4 most significant survival-predicting GDRGs, and patients with different expression levels of each of these genes had distinct survival outcomes. Finally, a nomogram composed of the GDRG signature, age, pharmacotherapy, radiotherapy, IDH mutations and MGMT promoter methylation was generated and validated in two large GBM cohorts to predict GBM prognosis. This study highlights the significant roles of...

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PMID: 32957084
DOI: 10.18632/aging.103695

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