Article
Contribution of DNA adenine methylation to gene expression heterogeneity in Salmonella enterica.
Nucleic acids research - 2 Dec 2020
Sánchez-Romero María A, Olivenza David R, Gutiérrez Gabriel, Casadesús Josep
Abstract excerpt
Expression of Salmonella enterica loci harboring undermethylated GATC sites at promoters or regulatory regions was monitored by single cell analysis. Cell-to-cell differences in expression were detected in ten such loci (carA, dgoR, holA, nanA, ssaN, STM1290, STM3276, STM5308, gtr and opvAB), with concomitant formation of ON and OFF subpopulations. The ON and OFF subpopulation sizes varied depending on the growth...
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