Article
Regulation of the Salmonella enterica std fimbrial operon by DNA adenine methylation, SeqA, and HdfR.
Journal of bacteriology - 1 Nov 2008
Jakomin Marcello, Chessa Daniela, Bäumler Andreas J, Casadesús Josep
Abstract excerpt
DNA adenine methylase (dam) mutants of Salmonella enterica serovar Typhimurium grown under laboratory conditions express the std fimbrial operon, which is tightly repressed in the wild type. Here, we show that uncontrolled production of Std fimbriae in S. enterica serovar Typhimurium dam mutants contributes to attenuation in mice, as indicated by the observation that an stdA dam strain is more competitive than a...
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