Renal Manifestations of Tuberous Sclerosis Complex

Abstract excerpt

gene. Disruption of either of these genes leads to impaired production of hamartin or tuberin proteins, leading to the manifestation of skin lesions, tumors, and seizures. TSC can manifest in multiple organ systems with the cutaneous and renal systems being the most commonly affected. These manifestations can secondarily lead to the development of hypertension, chronic kidney disease, and neurocognitive declines....

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Tuberous Sclerosis Complex Research
• Share to Genetic and Kidney Cyst Diseases
• Share to Renal cell carcinoma treatment