Article
Tuberous sclerosis complex.
Handbook of clinical neurology - 1 Jan 2015
Islam Monica P, Roach E Steve
Abstract excerpt
Tuberous sclerosis complex (TSC) is a neurocutaneous syndrome that can affect the brain, skin, eyes, kidneys, heart, and lungs. TSC alters cellular proliferation and differentiation, resulting in hamartomas of various organs, tumor formation, and altered neuronal migration. The phenotype is highly variable. Most individuals have seizures, commonly including infantile spasms, and there is variable intellectual...
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