Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

An integrative multi-omics approach reveals new central nervous system pathway alterations in Alzheimer’s disease

1 Apr 2021

Abstract excerpt

BACKGROUND: Multiple pathophysiological processes have been described in Alzheimer's disease (AD). Their inter-individual variations, complex interrelations, and relevance for clinical manifestation and disease progression remain poorly understood. We hypothesize that specific molecular patterns indicating both known and yet unidentified pathway alterations are associated with distinct aspects of AD pathology....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer's disease research and treatments
Share to Clusterin in disease pathology
Share to GDF15 and Related Biomarkers

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33794997
DOI: 10.1186/s13195-021-00814-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

An integrative multi-omics approach reveals new central nervous system pathway alterations in Alzheimer’s diseasePMID 33794997Read ↗

Brain cross-omics integration in Alzheimer’s diseaseSemantic proximity Read ↗

Brain high-throughput multi-omics data reveal molecular heterogeneity in Alzheimer’s diseaseSemantic proximity Read ↗

Integrated lipidomics and proteomics network analysis highlights lipid and immunity pathways associated with Alzheimer’s diseaseSemantic proximity Read ↗

Integrated multi-omics analysis of Alzheimer’s disease shows molecular signatures associated with disease progression and potential therapeutic targetsSemantic proximity Read ↗

Integration of aged brain multi-omics reveals cross-system mechanisms underlying Alzheimer’s disease heterogeneitySemantic proximity Read ↗

Data-driven biomarker analysis using computational omics approaches to assess neurodegenerative disease progressionSemantic proximity Read ↗

Integration of proteomics and metabolomics – insights into inflammation, metabolic dysregulation, and vascular aspects in ADSemantic proximity Read ↗

Predicting Alzheimer’s Disease with Multi-Omic Data: A Systematic ReviewSemantic proximity Read ↗

Multi‐Omics‐Based Autophagy‐Related Untypical Subtypes in Patients with Cerebral Amyloid PathologySemantic proximity Read ↗

Integrated lipidomics and proteomics network analysis highlights lipid and immunity pathways associated with Alzheimer’s diseaseSemantic proximity Read ↗

Genetic and Multi-omic Risk Assessment of Alzheimer’s Disease Implicates Core Associated Biological DomainsSemantic proximity Read ↗

Multi-Omics Integration of Transcriptomics and Metabolomics with Machine Learning Uncovers Novel Risk Factors for Alzheimer’s diseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.