Article
Hyperthyroidism and bone mineral density: Dissecting the causal association with Mendelian randomization analysis.
Clinical endocrinology - 1 Jan 2021
Deshmukh Harshal, Papageorgiou Maria, Aye Mo, England James, Abdalla Mohammed, Sathyapalan Thozhukat
Abstract excerpt
INTRODUCTION: Untreated hyperthyroidism is associated with accelerated bone turnover, low bone mineral density (BMD) and increased susceptibility to fragility fractures. Although treatment appears to improve or even reverse some of these adverse skeletal effects, there is limited guidance on routine BMD assessment in hyperthyroid patients following treatment. By using Mendelian randomization (MR) analysis, we...
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