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Mechanical stress regulates autophagic flux to affect apoptosis after spinal cord injury

17 Sept 2020

Abstract excerpt

Increased mechanical stress after spinal cord injury (SCI) expands the scope of nerve tissue damage and exacerbates nerve function defects. Surgical decompression after SCI is a conventional therapeutic strategy and has been proven to have neuroprotective effects. However, the mechanisms of the interaction between mechanical stress and neurons are currently unknown. In this study, we monitored intramedullary...

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PMID: 32945105
DOI: 10.1111/jcmm.15863

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