Article
Most frequent South Asian haplotypes of ACE2 share identity by descent with East Eurasian populations.
PloS one - 1 Jan 2020
Srivastava Anshika, Pandey Rudra Kumar, Singh Prajjval Pratap, Kumar Pramod, Rasalkar Avinash Arvind, Tamang Rakesh, van Driem George, Shrivastava Pankaj, Chaubey Gyaneshwer
Abstract excerpt
It was shown that the human Angiotensin-converting enzyme 2 (ACE2) is the receptor of recent coronavirus SARS-CoV-2, and variation in this gene may affect the susceptibility of a population. Therefore, we have analysed the sequence data of ACE2 among 393 samples worldwide, focusing on South Asia. Genetically, South Asians are more related to West Eurasian populations rather than to East Eurasians. In the present...
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