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Article

Causal Pathways from Body Components and Regional Fat to Extensive Metabolic Phenotypes: A Mendelian Randomization Study.

Obesity (Silver Spring, Md.) - 1 Aug 2020

Si Shucheng, Tewara Marlvin Anemey, Li Yunxia, Li Wenchao, Chen Xiaolu, Yuan Tonghui, Liu Congcong, Li Jiqing, Wang Bojie, Li Hongkai, Hou Lei, Wang Qing, Xue Fuzhong

Abstract excerpt

OBJECTIVE: The aim of this study was to explore the causal effects and pathways from body components to extensive metabolic phenotypes. METHODS: Summarized data including 24 metabolic phenotypes from 10 consortiums were used to perform univariate, multivariable, and bidirectional Mendelian randomization analysis based on the network design. RESULTS: For metabolically related biomarkers, a 1-SD increase in body...

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PMID: 32935532
DOI: 10.1002/oby.22857

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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