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Article

Analysis of ACE2 Genetic Variability among Populations Highlights a Possible Link with COVID-19-Related Neurological Complications.

Genes - 3 Jul 2020

Strafella Claudia, Caputo Valerio, Termine Andrea, Barati Shila, Gambardella Stefano, Borgiani Paola, Caltagirone Carlo, Novelli Giuseppe, Giardina Emiliano, Cascella Raffaella

Abstract excerpt

Angiotensin-converting enzyme 2 (ACE2) has been recognized as the entry receptor of the novel severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2). Structural and sequence variants in ACE2 gene may affect its expression in different tissues and determine a differential response to SARS-Cov-2 infection and the COVID-19-related phenotype. The present study investigated the genetic variability of ACE2 in...

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Identifiers

PMID: 32635188
DOI: 10.3390/genes11070741
PMCID: PMC7397291

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