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Article

Meta-GWAS of Pig Semen Quality Traits Reveals Conserved Genes Regulating Mammalian Fertility.

Advanced science (Weinheim, Baden-Wurttemberg, Germany) - 1 Mar 2026

Lin Qing, Cai Xiaodian, Zhong Zhanming, Li Tingting, Chen Xinyou, Ayalew Wondossen, Xu Zhiting, Wei Chen, Zhang Xiaoke, Cheng Hong, Zhang Zhenyang, Li Xuehua, Tang Yongjie, Chen Siqian, Zhou Jun, Si Jinglei, Wu Xibo, Ning Chao, Wang Qishan, Pan Yuchun, Gao Yahui, Li Jiaqi, Yu Ying, Zhang Zhe, Zhao Yunxiang, Fang Lingzhao, Zhang Zhe

Abstract excerpt

Semen quality serves as a vital indicator of male fertility, yet its underlying genetic and regulatory mechanisms remain poorly understood. Here, 1.15 million records of six semen quality traits from 14 210 boars in four distinct breeds were collected. These traits have low to moderate heritability (0.12-0.26), and are genetically correlated with growth traits like average daily gain. Genome-wide association...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41504393
DOI: 10.1002/advs.202515203
PMCID: PMC13042736

Genes

ADRA2A
AURKAIP1
LEFTY2
NAXE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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