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Article

Successful treatment of nonsmall cell lung cancer patients with leptomeningeal metastases using whole brain radiotherapy and tyrosine kinase inhibitors.

Journal of cancer research and therapeutics - 1 Jan 2000

Sakaguchi Masakuni, Maebayashi Toshiya, Aizawa Takuya, Ishibashi Naoya, Saito Tsutomu

Abstract excerpt

The efficacy of treatments in patients with nonsmall cell lung cancer (NSCLC) with leptomeningeal metastases (LMs) remains unclear. Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) play an important role in the treatment of patients with NSCLC. However, few studies have investigated the efficacy of combination therapy with TKIs and whole brain radiotherapy (WBRT) in patients with NSCLC/LM....

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Identifiers

PMID: 32930144
DOI: 10.4103/jcrt.JCRT_1343_16

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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