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Article

Long-term outcome after multidisciplinary approach for leptomeningeal carcinomatosis in a non-small cell lung cancer patient with poor performance status.

Internal medicine (Tokyo, Japan) - 1 Jan 2011

Nagano Tatsuya, Kotani Yoshikazu, Kobayashi Kazuyuki, Hatakeyama Yukihisa, Hori Suya, Kasai Daisuke, Funada Yasuhiro, Nishimura Hideki, Kondoh Takeshi, Nishimura Yoshihiro

Abstract excerpt

The present study describes a case of a 60-year-old Japanese man who was histologically diagnosed with lung adenocarcinoma harboring L858R mutation of epidermal growth factor receptor. He was successfully treated with gefitinib, but eventually developed leptomeningeal carcinomatosis. He underwent ventriculoperitoneal shunting for hydrocephalus and received erlotinib in place of gefitinib with concurrent whole...

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Identifiers

PMID: 22185996
DOI: 10.2169/internalmedicine.50.5903

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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